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Coumadin toxicity treatment

 

You and your healthcare provider should decide if you will take coumadin and breastfeed.

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Select the initial dose based on the expected maintenance dosetaking into account the above factorsModify this dose based on consideration of patient-specific clinical factorsConsider lower initial and maintenance doses for elderly and/or debilitated patients and in Asian patientssee Use In Specific Populations and CLINICAL PHARMACOLOGYRoutine use of loading doses is not recommended as this practice may increase hemorrhagic and other complications and does not offer more rapid protection against clot formation.

The prothrombin timePT or protimetest will tell your doctor how fast your blood is clotting and whether your dose needs to be changedIllnessdietchanges to your medicinesand physical activities may affect the results.

For patients with a DVT or PE secondary to a transientreversiblerisk factortreatment with warfarin for 3 months is recommendedFor patients with an unprovoked DVT or PEtreatment with warfarin is recommended for at least 3 monthsAfter 3 months of therapyevaluate the risk-benefit ratio of long-term treatment for the individual patientFor patients with two episodes of unprovoked DVT or PElong-term treatment with warfarin is recommendedFor a patient receiving long-term anticoagulant treatmentperiodically reassess the risk-benefit ratio of continuing such treatment in the individual patient.

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